I have been commenting all the assignments of my students, only to find out that there is no way to download my own feedback! I know that I can download individual comments, one by one. It would be much easier to download a table with all the assignment comments, all at once. We need this for accreditation of engineering programs. C'mon, Canvas! It's such a basic feature! Everyday I'm more disappointed about Canvas and the absolute lack of technical support.
Design Engineering Canvas Pdf Download
ACD Canvas is a design program from ACD Systems for producing technical graphics. The program is dedicated toward aerospace, energy and engineering applications, arranging objects on your screen with precision levels measured in hundredths of a micron. Once your business has created a design in Canvas, you can edit it further in Adobe Illustrator, although Illustrator does not support Canvas's CVX file type. To export from Canvas to Illustrator, use a file type that both support, such as PDF.
Visio is a diagraming tool that makes it easy and intuitive to create flowcharts, diagrams, org charts, floor plans, engineering designs, and more by using modern templates with the familiar Office experience. On this page, you can access some of the top templates and sample diagrams available in Visio, or request ones that you want.
We report the development and deployment of web-based bioCAD software, DeviceEditor, which provides a graphical design environment that mimics the intuitive visual whiteboard design process practiced in biological laboratories. The key innovations of DeviceEditor include visual combinatorial library design, direct integration with scar-less multi-part DNA assembly design automation, and a graphical user interface for the creation and modification of design specification rules. We demonstrate how biological designs are rendered on the DeviceEditor canvas, and we present effective visualizations of genetic component ordering and combinatorial variations within complex designs.
Towards addressing these unmet design needs, we have developed DeviceEditor, a bioCAD canvas that enables researchers to spatially organize abstractions of biological components. DeviceEditor assists the aggregation and arrangement of the DNA sequences of genetic components (e.g., ribosomal-binding sites, promoters and terminators, and metabolic pathway genes) to be assembled towards a desired functionality. DeviceEditor ensures that designs are "correct-by-construction", because within its confines researchers are prevented from performing invalid operations (e.g. referencing DNA base-pair 500 within a 100 base-pair sequence). To the best of our knowledge, DeviceEditor is the first bioCAD tool that visualizes combinatorial DNA library design, provides a graphical user interface for the creation and modification of design specification rules, and is directly integrated with scar-less multi-part DNA assembly design automation. Taken together, these innovations benefit researchers and their institutions through correct-by-construction design, the automation of tedious tasks, design reuse, and the minimization of DNA assembly costs.
The DeviceEditor bioCAD canvas provides a web-based visual design environment (Figure 1) that mimics the familiar whiteboard design process practiced in biological laboratories. An online user's manual [23] provides an introduction to bioCAD, an overview of DeviceEditor functionality, and step-by-step how-to video demonstrations.
DeviceEditor design canvas. Screenshot of the browser-based DeviceEditor user interface [24]: (top left) buttons for activating the j5 controls dialog box and setting DeviceEditor properties, (left panel) palette of standardized SBOLv part icons, (center) drag-and-drop design canvas with part icons and a collection object (white oval with vertical lines demarking bins), and (right panel) information detail for the selected part or collection.
Mapping a DeviceEditor part icon to an annotated DNA sequence. A new part icon on the design canvas (top left) is created by clicking on the desired SBOLv icon (here "Origin of Replication") in the left panel of the user interface (Figure 1). At this point, a DNA sequence has yet to be mapped to the part icon. In a separate browser-tab or software application, the desired portion of a DNA sequence (here the pBbS8c-rfp backbone [27] spanning from Xho I to EcoR I) is selected and copied (top right) to the clipboard. Third-party software (here VectorEditor) may embed meta-data (including jbei-seq format [28] sequence data) into the clipboard along with the plain-text DNA sequence selection (see Methods). Returning to DeviceEditor, the copied DNA sequence is pasted (mapped) from the clipboard onto the part icon. Clipboard meta-data provides DeviceEditor with the selected start and stop base pairs (here 1934 to 1215) within the circular source sequence, along with the source's name (here pBbS8c-rfp), entire sequence, and feature annotations (displayed in the "Source Data" field; bottom left). If the third-party software (e.g. ApE [29]) does not embed this meta-data, the sequence annotations are not transferred to DeviceEditor, and the user must specify the source name and the selected start and stop base-pairs within the copied sequence. The user may alternatively map a Genbank-format sequence file to the part icon, which preserves the source name and feature annotations. The name for the part icon (here "pBbS8c_EcoRI_XhoI_vector_backbone") is specified, along with whether the part is associated with the reverse complement of the selected sequence. The "Done" button is clicked, the part icon has now been named, and the desired annotated DNA sequence has been mapped to the part icon (bottom right).
Example biological designs rendered on the DeviceEditor canvas. (A) pNJH00010 [12] consists of seven components: the pBbS8c-rfp backbone spanning from Xho I to EcoR I (blue highlight, bottom left), the RBS sequence from pBbS8c-rfp (purple highlight, bottom left), gfp uv from its 5' end to its Xho I site (blue highlight, bottom right), a silent mutation in gfp uv 's Xho I site (star), gfp uv between its Xho I and BamH I sites (purple highlight, bottom right), a silent mutation in gfp uv 's BamH I site (star), and gfp uv _sig.pep from its BamH I site to its 3' end (blue highlight, bottom right). These components are arranged from left to right in their 5' to 3' order in pNJH00010 (top). The corresponding SBOLv icon is presented immediately above each component. (B) To reconstitute the design in (A), each of the component sequences is mapped to a part icon (as in Figure 2), and arranged from left to right in 5' to 3' order as in (A) in a 7-bin collection object (white oval with vertical blue lines demarking bins), with each part icon in its own bin. This DeviceEditor design has been saved in Additional file 1. (C) The combinatorial design for plasmids pRDR000001-pRDR000008 [12] consists of nine components, including the pNJH00010 backbone, two N-terminal signal peptides (sig1 and sig2), two Gly/Ser linkers (long and short), the gfp uv mutant from pNJH00010, two 5' ssrA tags (standard and enhanced), and a 3' ssrA tag. These components are arranged from left to right from 5' to 3', with interchangeable components arranged from top to bottom. (D) Each of the component sequences in (C) is mapped to a part icon, and these part icons are then arranged from left to right as in (C) in a 6-bin collection object, with interchangeable part icons in the same bin. Each bin, now demarcated with purple lines indicating a combinatorial design, is then named according to the category of parts it contains (bottom) This DeviceEditor design has been saved in Additional file 2.
Adding Eugene design specification rules. (A) Graphical user interface for creating and modifying rules. A part icon (here "short", bottom left) on the design canvas is clicked, followed by the "Add Rule" button in the right panel of the user interface (bottom right). The name for the rule (here "rule3") is specified, and one of three Eugene operators (NOTMORETHAN, WITH or NOTWITH) is selected (here "WITH"). For the NOTMORETHAN operator, the maximum number of times the part may be present in a single construct is specified. For the WITH or NOTWITH operators, the other part icon on the design canvas (Operand 2, here "sig1") that should or should not be present in a single construct, respectively, with the selected part icon (Operand 1, here "short") is chosen. The list of Eugene rules associated with the selected part icon is shown in the right panel of the user interface (right). Part icons with associated Eugene rules are visually identified on the design canvas by an orange circle indicator light at bottom right, and part icons with specified forced assembly strategies are distinguished with a blue (bin consensus-matching assembly strategy) or a red (bin consensus-breaking assembly strategy) rectangle indicator at top left. (B) Importing Eugene rules from a file. From the "File" pull-down menu of the user interface (Figure 1, top left), "Import Eugene Rules" is clicked and a Eugene rules file (e.g. Additional file 3) is selected. The Eugene Rules Import dialog displays imported rules in green, rules identical to current rules in black, imported rules with names conflicting with current rules displayed in red (alternative names are auto-generated for the imported rules to resolve conflicts), and ignored rules (e.g. comment lines or rules with invalid operators or operands not present in the current design) in light grey. Importing a set of Eugene rules facilitates the batch creation of multiple rules for complex designs (Figure 5). 2ff7e9595c